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Primary Cells

Human Sebocytes

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Adult normal Primary Sebocytes are a vital research tool for a variety of applications from acne, seborrhoea and other sebaceous gland-related diseases studies in skin biology/cosmetic programs. AcceGen isolates normal human sebocytes from fully consented donors, under IRB approval. The cells are QC for purity and function using Keratin-7 and MUC-1 Staining and lipid accumulation. […]
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Species

Human

Cat.No

ABC-TC3794

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Sebocyte

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Skin Cells

Description

Human Sebocytes are primary cells isolated from normal human facial skin tissue, specifically derived from sebaceous glands. These cells exhibit epithelial morphology with adherent culture properties. Following primary culture, the cells are cryopreserved and typically maintain viability for limited passages in vitro. Functionally, sebocytes synthesize and secrete sebum, a lipid-rich mixture containing squalene, wax esters, and free fatty acids, which is critical for skin lubrication and barrier integrity. Their dysregulation is implicated in sebaceous gland-related pathologies such as acne vulgaris and seborrhoea, where excessive lipid production and inflammatory cytokine release (e.g., IL-8, TNF-α) contribute to disease pathogenesis. These cells express characteristic markers including Keratin-7 and MUC-1.

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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • Human SebocytesHuman sebocytes serve as a valuable in vitro model for fundamental research into the function and regulation of sebaceous cells, as well as a tool for exploring treatments of sebaceous gland-related conditions like acne and seborrhea. With their application in various studies, these cells shed light on sebaceous gland activity and its cellular-level control. Moreover, they enable the evaluation of agents’ inhibitory effects on sebocyte activity, contributing to a deeper understanding of these conditions and potential therapeutic strategies.

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