For research use only
| Cat No. | ABC-TC3794 |
| Product Type | Skin Cells |
| Cell Type | Sebocyte |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human Sebocytes are primary skin cells essential for dermatology research, lipid metabolism, acne studies, and sebaceous gland biology investigation.
Human Sebocytes are specialized epithelial cells derived from sebaceous glands, isolated from normal human facial skin tissue. These lipid-rich, adherent cells exhibit epithelial morphology with prominent vacuoles. Following primary culture, the cells are cryopreserved and typically maintain viability for limited passages in vitro. Functionally, sebocytes are responsible for synthesizing and secreting sebum, a lipid-rich mixture containing squalene, wax esters, and free fatty acids, which is critical for skin lubrication and barrier integrity. Their dysregulation is implicated in sebaceous gland-related pathologies such as acne vulgaris and seborrhoea, where excessive lipid production and inflammatory cytokine release (e.g., IL-8, TNF-α) contribute to disease pathogenesis. Sebocytes express characteristic markers such as keratin 7, epithelial membrane antigen (EMA), and peroxisome proliferator-activated receptor gamma (PPARγ). They play critical roles in skin physiology, including innate immunity, inflammation regulation, and microbial defense.
| Product Code | Human Sebocytes, Sebaceous Gland Cells, Sebaceous Epithelial Cells, Sebum-Producing Cells |
| Species | Human |
| Cat.No | ABC-TC3794 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Sebocyte |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Skin Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Human sebocytes serve as a valuable in vitro model for fundamental research into the function and regulation of sebaceous cells, as well as a tool for exploring treatments of sebaceous gland-related conditions like acne and seborrhea. With their application in various studies, these cells shed light on sebaceous gland activity and its cellular-level control. Moreover, they enable the evaluation of agents’ inhibitory effects on sebocyte activity, contributing to a deeper understanding of these conditions and potential therapeutic strategies.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
