Human Subcutaneous Preadipocytes and Adipocytes

Description

Human Subcutaneous Preadipocytes and Adipocytes are isolated from human subcutaneous adipose tissue. Cryopreserved at early passage, preadipocytes exhibit a fibroblast-like morphology in adherent monolayers, while mature adipocytes are non-adherent and non-proliferative. They function in energy storage, lipid metabolism, and secretion of adipokines, with relevance to obesity, type 2 diabetes, and metabolic syndrome. They express the preadipocyte surface marker CD29, and differentiated adipocytes are identified by perilipin and fatty acid-binding protein 4 (FABP4). Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.