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Tumor Cell Lines

HuP-T3

  • For research use only

Cat No.

ABC-TC497S

Product Type

Human Pancreas Cancer Cell Lines

Cell Type

Epithelial

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pancreas

Product Code

HUP-T3; Hu-P-T3; HuPT3; HupT3; HUPT3

HuP-T3 pancreatic adenocarcinoma cells from 66-year-old male show KRAS, TP53, MSH6 mutations, adherent growth, tumorigenic, key for pancreatic cancer.

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Description

HuP-T3 is a human pancreatic adenocarcinoma cell line derived from the ascites fluid of a 66-year-old Japanese male patient. This epithelial-like cell line exhibits adherent growth properties and demonstrates a doubling time of approximately 40–50 hours. Genomic profiling reveals critical mutations in KRAS (p.Gly12Arg), TP53 (p.Arg282Trp), and MSH6 (p.Lys1358fs*2. When xenografted into nude mice, HuP-T3 form poorly differentiated adenocarcinomas, confirming their tumorigenic potential. These characteristics position HuP-T3 as a valuable and physiologically relevant tool for investigating pancreatic cancer pathogenesis and therapeutic response mechanisms.
Product Code

HUP-T3; Hu-P-T3; HuPT3; HupT3; HUPT3

Species

Human

Cat.No

ABC-TC497S

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pancreas

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Pancreas Cancer Cell Lines

Application

  • The HuP-T3 cell line serves as a valuable model for pancreatic cancer research, particularly in studies focused on tumor invasion, migration, and metastasis.. It offers an effective platform to explore the molecular signaling pathways such as those involving KRAS and p53, which drive the aggressive behavior of pancreatic tumors. HuP-T3 cells are widely used in preclinical drug screening, enabling researchers to evaluate the efficacy of novel anticancer compounds and targeted therapies. Furthermore, its defined genetic alterations make it ideal for studying the cellular response to genotoxic stress, supporting the development of precision oncology strategies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring HuP-T3

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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