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| Product Code | Jhh-7; JHH7; FLC-7; FLC7; Functional Liver Cell-7 |
| Species | Human |
| Cat.No | ABC-TC0475 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Hepatocellular Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Liver Cancer Cell Lines |
JHH-7 is an hepatocellular carcinoma cell line that was originally isolated from the liver tissue of a 53-year-old male patient with Hepatocellular Carcinoma (HCC) accompanied by cirrhosis, The serum test indicate that patient are HBsAg(+)，HBsAb(-)，HBeAg(-)，HBeAb(+)，HBc-Ab(+). JHH-7 exhibits epithelial-like morphology and adherent culture properties. JHH-7 cell are tested positive for Hepatitis B virus genome by real-time PCR test, but the integrated hepatitis B virus genome is incomplete. Therefore its unable to produce hepatitis B virus. JHH-7 are highly express various hepatocellular carcinoma cell associated gene and protein such as Alpha-fetoprotein(AFP), Carcinoembryonic antigen(CEA), and Fibrinogen.
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The JHH-7 cell line has valuable applications in studying hepatocellular carcinoma development, particularly in non-A/non-B hepatitis virus research. It serves as a model for investigating the integrated hepatitis B virus genome in hepatocellular carcinoma cells. Moreover, researchers can utilize this cell line to evaluate the potential of drugs or biochemicals in inducing apoptosis or inhibiting intrahepatic spread of hepatocellular carcinoma, offering insights into potential therapeutic interventions for this aggressive liver cancer.
