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Tumor Cell Lines

MDA-MB-175-VII

  • BSL

    1

  • 382
This is one of a series of breast tumor lines isolated from pleural effusions and characterized by R. Cailleau and associates in 1973. The cells grow a monolayer of round loosely adherent cells.
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Home | Tumor Cell Lines | Human Tumor Cell Lines | MDA-MB-175-VII
Product Code

MDA MB 175 VII; MDA-MB-175VII; MDAMB175VII; MDA-MB-175; MDAMB175; MDA-175; MDA175; MD Anderson-Metastatic Breast-175-VII
Species

Human
Cat.No

ABC-TC0650
Product Category Tumor Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 ℃
Source Organ

Breast
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Human Breast Cancer Cell Lines

Description

Brightfield micrograph of MDA-MB-175-VII, showing adherent growth, 20X magnification.
MDA-MB-175-VII is a human breast invasive ductal carcinoma (IDC) cell line that was originally isolated from the pleural effusion of a 56-year-old Black or African American female patient with invasive breast carcinoma. MDA-MB-175-VII exhibits epithelial-like morphology and semi-adherent culture properties. The stemline karyotype model number of MDA-MB-175-VII is 84 with a range from 82 to 89. This cell line is aneuploid; it is displaying chromosomal counts within the hypertetraploid to near-tetraploid range (PMID: 18516279). MDA-MB-175-VII is tumorigenic and metastasis. After 10^7 cells were inoculated subcutaneously in nude mice, all samples developed tumors within 21 days.
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Application

  • MDA-MB-175-VII cell line serves as a valuable asset in cancer research. It aids in identifying high-risk factors associated with breast cancer. Additionally, it facilitates the identification of pivotal genes and expressed proteins that drive breast cancer cell proliferation, while also enabling preclinical assessments of specific antibody effectiveness. The cell line’s utility extends to evaluating the apoptotic and cytotoxic impacts of different drugs, enhancing our understanding of potential treatments.

Quality Control Report

  • Test Item
  • Flow Cytometry
  • Result
  • MDA-MB-436 (NC)MDA-MB-175 VII

    Flow cytometry plot of MDA-MB-436 (NC), showing EGFR expression to be 0.63%.Flow cytometry plot of MDA-MB-175-VII, showing EGFR expression to be 38.5%.

    The percentage of EGFR expression in MDA-MB-175-VII Cell line was detected by flow cytometry to be approximately 38.5%.

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