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Tumor Cell Lines

MDA-MB-175-VII

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    1

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This is one of a series of breast tumor lines isolated from pleural effusions and characterized by R. Cailleau and associates in 1973. The cells grow a monolayer of round loosely adherent cells.
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Product Code

MDA MB 175 VII; MDA-MB-175VII; MDAMB175VII; MDA-MB-175; MDAMB175; MDA-175; MDA175; MD Anderson-Metastatic Breast-175-VII

Species

Human

Cat.No

ABC-TC0650

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃

Source Organ

Breast

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Breast Cancer Cell Lines

Description

MDA-MB-175-VIIMDA-MB-175-VII is a human breast invasive ductal carcinoma (IDC) cell line that was originally isolated from the pleural effusion of a 56-year-old Black or African American female patient with invasive breast carcinoma. MDA-MB-175-VII exhibits epithelial-like morphology and semi-adherent culture properties. The stemline karyotype model number of MDA-MB-175-VII is 84 with a range from 82 to 89. This cell line is aneuploid; it is displaying chromosomal counts within the hypertetraploid to near-tetraploid range (PMID: 18516279). MDA-MB-175-VII is tumorigenic and metastasis. After 10^7 cells were inoculated subcutaneously in nude mice, all samples developed tumors within 21 days.

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Citation

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Application

  • MDA-MB-175-VII cell line serves as a valuable asset in cancer research. It aids in identifying high-risk factors associated with breast cancer. Additionally, it facilitates the identification of pivotal genes and expressed proteins that drive breast cancer cell proliferation, while also enabling preclinical assessments of specific antibody effectiveness. The cell line’s utility extends to evaluating the apoptotic and cytotoxic impacts of different drugs, enhancing our understanding of potential treatments.

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