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Mouse Hippocampal Astrocytes | ||||
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| Product Name | Mouse Hippocampal Astrocytes | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC3915 | Species | Mouse | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | Mouse hippocampal astrocytes are thought to form a highly coupled network. They contribute to neural functioning in the hippocampus, which is crucial for spatial memory formation.
Why choose Mouse Hippocampal Astrocytes from AcceGen? Choosing Mouse Hippocampal Astrocytes from AcceGen offers several advantages. AcceGen provides high-quality astrocytes isolated from the hippocampus of neonate day two mice and cryopreserved at an early stage (P1) with a substantial cell count of >0.5 million cells per vial. These astrocytes express GFAP, a marker for astrocytic identification, and are free from various contaminants such as HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. Moreover, AcceGen’s astrocytes have the potential to be expanded for five population doublings using AcceGen’s recommended culture conditions. This ensures a reliable and abundant supply of mouse hippocampal astrocytes for research purposes. | |||
| Disease | Normal | |||
| Source Organ | Brain | |||
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. | |||
| Recommended Medium And Supplement | ABM-TM3915 Mouse Astrocytes Hippocampal Medium Kit | |||
| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
| Application | FOR RESEARCH USE ONLY Investigating mouse hippocampal astrocytes offers valuable insights into their localized functions, molecular regulation, and physiological characteristics. By studying these cells, researchers can unravel the molecular controls that shape astrocytic fate and physiology, as well as understand how evolutionary changes in astrocytes impact higher cognitive functions. Furthermore, exploring the role of astrocytes in neural information processing and cognition enhances our understanding of brain function. Although much of our knowledge about astrocytes comes from in vitro studies, the ongoing utilization of astrocyte culture as a research tool enables the exploration of the diverse properties of astrocytes and their contributions to brain function. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Cell Type | Astrocyte | |||
| Growth Mode | Adherent | |||
| Product Type | Mouse Primary Cells | |||
| Product Image |  | |||
Disrupting this astrocyte network alters neuronal excitability and synaptic transmission in the hippocampus. In mouse models, inhibiting vesicle release from hippocampal astrocytes impairs recognition memory, while chemogenetic activation enhances contextual fear memory. These findings highlight the significant role of hippocampal astrocytes in hippocampus-dependent brain functions and behaviors. Their close interaction with neurons facilitates information processing and influences memory formation in the hippocampus.- ONLINE INQUIRY
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