For research use only
| Cat No. | ABC-TC3922 |
| Product Type | Mouse Primary Cells |
| Cell Type | Cartilage Cell |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cartilage |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Mouse cartilage cells, 4-week ICR mouse.
Mouse Cartilage Cells are primary chondrocytes isolated from the articular cartilage tissue of healthy mice. These mouse cells are responsible for maintaining cartilage extracellular matrix. Morphologically, they exhibit a rounded or polygonal shape and grow in an adherent manner, often forming clusters in culture. Functionally, cartilage cells synthesize key extracellular matrix components including collagen type II and proteoglycans, crucial for cartilage elasticity and load-bearing capacity. Dysregulation of chondrocyte function has been implicated in cartilage disorders such as osteoarthritis and chondrodysplasia. The cells express collagen type II and aggrecan, while karyotype analysis shows normal diploidy. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Mouse Cartilage Cells, Murine Chondrocytes, Cartilage-Derived Cells (Mouse), Primary Cartilage Cells |
| Species | Mouse |
| Cat.No | ABC-TC3922 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Cartilage Cell |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cartilage |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Mouse Cartilage Cells can be used as an in vitro cell model to study the pathogenesis of cartilage degeneration and joint diseases, such as osteoarthritis, rheumatoid arthritis, and chondrodysplasias. For example, by investigating their synthesis and degradation of extracellular matrix components (e.g., collagen II, aggrecan) in response to inflammatory cytokines or mechanical stress, researchers can explore ECM remodeling dynamics, cytokine-mediated catabolic pathways, and mechanotransduction responses. This supports discovery research and molecular target identification related to cartilage-associated joint disorders associated with aberrant chondrocytic physiology in joint homeostasis maintenance and pathological dysregulation in disease pathogenesis.
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