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Primary Cells

Mouse Renal Mesangial Cells

  • For research use only

Cat No.

ABC-TC3935
Product Type

Mouse Primary Cells
Cell Type

Mesangial
Species

Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Kidney
Disease

Normal
Storage

Liquid Nitrogen

Mouse Renal Mesangial Cells (MRMC) are isolated from mouse kidneys.

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  • Mouse Renal Mesangial Cells
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | Mouse Renal Mesangial Cells

Description

Mouse Renal Mesangial Cells are primary cells isolated from the renal glomerular tissue of healthy mice and located within the central portion of the glomerular tuft between capillary loops. They exhibit a spindle-shaped to stellate morphology with adherent growth. Functionally, mesangial cells regulate the intraglomerular capillary flow and ultrafiltration surface through their contraction and release of growth factors and vasoactive agents. Their dysregulation is linked to glomerulonephritis, diabetic kidney disease, and lupus nephritis. The cells express vimentin. These cells have limited proliferative capacity in vitro. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

MRMC
Species

Mouse
Cat.No

ABC-TC3935
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Mesangial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Mouse Renal Mesangial Cells serve as a relevant in vitro cellular model for investigating the underlying pathophysiological processes of glomerular diseases, such as lupus nephritis and diabetic nephropathy. For example, by investigating their proliferation, extracellular matrix (ECM) synthesis, and response to inflammatory cytokines or metabolic stress, researchers can explore molecular pathways underlying mesangial dysfunction. This provides insight into mesangial cells’ physiological roles in maintaining glomerular structure and their pathological alterations in disease, supporting discovery research and molecular target identification for renal fibrosis and immune-mediated kidney disorders.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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