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| Product Code | MRC5; MRC 5; MRCV; MRC-V |
| Species | Human |
| Cat.No | ABC-TC0702 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lung Cell Lines |
MRC-5 is a human lung fibroblast cell line that was originally isolated from the normal lung tissue of a 14-week-old male fetus. MRC-5 exhibits fibroblast-like morphology and adherent culture properties. This cell line is a normal diploid with a karyotype of 46, XY. The modal chromosome number is 46, with 70% of cells showing this count and a polyploidy rate of 3.6%. MRC-5 cells are non-tumorigenic.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
MRC-5 cells enable vaccine production against hepatitis A, varicella, and rabies and support viral research by studying replication/infection mechanisms of poliovirus 1, herpes simplex virus, and SARS-CoV-2 for antiviral development. They facilitate cancer research investigating tumor microenvironments and cancer-fibroblast interactions while offering potential stem cell applications due to fibroblast-like morphology and differentiation capacity. These cells further serve in biopharmaceutical/vaccine manufacturing and provide PCR control material via gDNA products to assess inhibition in bioproduction processes.
