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Tumor Cell Lines

IMR-90

  • For research use only

Cat No.

ABC-TC0451

Product Type

Human Lung Cell Lines

Species

Human

Growth Conditions

37 ℃, 5% CO2

Product Code

IMR90, IMR 90, imr-90

Tumorigenecity: Isoenzyme: G6PD,BHistopathology: normalSubculture: Split ratio: Media change: Reverse transcritase: negativeProduction

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Description

IMR-90 is a human diploid fibroblast cell strain originally derived from normal lung tissue of a 16-week-old female fetus. It exhibits typical fibroblast-like morphology with elongated, spindle-shaped cells and grows as adherent monolayers under standard culture conditions. IMR-90 cells maintain a normal diploid karyotype. IMR-90 cell line has been widely used to study cellular aging and senescence pathways, including the accumulation of senescent phenotypes and DNA damage responses during in vitro aging. They are also recognized for expressing structural proteins of the cytoskeleton and junctional complexes typical of lung fibroblasts. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

IMR90, IMR 90, imr-90

Species

Human

Cat.No

ABC-TC0451

Product Category

Tumor Cell Lines

Size/Quantity

1 vial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Lung Cell Lines

Application

  • IMR-90 cells are used as an in vitro model of normal human lung fibroblasts for investigating cellular aging, senescence mechanisms, cytoskeletal dynamics, and gene regulation in non-malignant contexts. They support studies of senescence-associated pathways, DNA damage responses, and epigenomic regulation in normal human diploid cells, providing contrast to transformed cancer cell models.

Citation

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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