For research use only
| Cat No. | ABC-TC0702 |
| Product Type | Human Lung Cell Lines |
| Cell Type | Fibroblast |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Normal |
| Product Code | MRC5; MRC 5; MRCV; MRC-V |
Discover MRC-5 human lung fibroblast cell line for toxicology, aging, and viral infection research, enabling normal cell model applications.
MRC-5 (also commonly abbreviated as MRC5) is a human lung fibroblast cell line derived from the normal lung tissue of a 14-week-old male fetus. These adherent, spindle-shaped cells exhibit typical fibroblast morphology and a finite lifespan, undergoing senescence after a defined number of population doublings. MRC-5 cells maintain a normal diploid karyotype, express fibroblast markers such as vimentin, and synthesize extracellular matrix components including collagen. They demonstrate contact inhibition and lack tumorigenic potential, making them a reliable model for normal human fibroblast biology. MRC-5 cells are widely employed in studies of cellular aging, respiratory physiology, viral vaccine production, and drug toxicity assessment due to their physiological relevance and stable growth characteristics.
| Product Code | MRC5; MRC 5; MRCV; MRC-V |
| Species | Human |
| Cat.No | ABC-TC0702 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lung Cell Lines |
MRC-5 cells enable vaccine production against hepatitis A, varicella, and rabies and support viral research by studying replication/infection mechanisms of poliovirus 1, herpes simplex virus, and SARS-CoV-2 for antiviral development. They facilitate cancer research investigating tumor microenvironments and cancer-fibroblast interactions while offering potential stem cell applications due to fibroblast-like morphology and differentiation capacity. These cells further serve in biopharmaceutical/vaccine manufacturing and provide PCR control material via gDNA products to assess inhibition in bioproduction processes.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
MRC-5 is a human diploid fibroblast cell line derived from lung tissue of a 14-week-old male fetus. It is widely used in vaccine production, virology research, and cytotoxicity studies due to its stable growth and normal karyotype.
