Plateable DOG (Beagle) Hepatocytes

Description

Plateable DOG (Beagle) Hepatocytes are isolated from liver tissue of the beagle and are cryopreserved after primary culture. They express α-fetoprotein (AFP), HepPar-1 antigen and arginase-1. These hepatocytes are extensively used in pharmacokinetic and toxicological research to evaluate drug metabolism, hepatotoxicity, and liver enzyme activity in canine models. Their use supports veterinary drug development and comparative studies across species. They maintain the capacity to attach and spread in vitro under appropriate culture conditions, making them suitable for short-term liver function assays. Due to their limited proliferative potential, these cells should be handled gently and protected from repeated freeze-thaw cycles. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.