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Primary Cells

Rat Cardiac Cells-Neonatal

  • For research use only

Cat No.

ABC-TC4104
Product Type

Rat Primary Cells
Cell Type

Cardiac Cell
Species

Rat
Growth Conditions

37 ℃, 5% CO2
Source Organ

Heart
Disease

Normal
Storage

Liquid Nitrogen

Rat primary cardiac cells (RPCACs) are isolated from heart tissue of 1-day-old neonatal Sprague-Dawley rats.

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Description

Neonatal Rat Cardiac Cells (NRVMs) are primary cells isolated from the ventricles of neonatal rats. These cells exhibit the characteristic elongated, striated morphology of cardiomyocytes and display spontaneous, rhythmic contractions in culture. Functionally, NRVMs demonstrate well defined electrophysiological properties including L and T type calcium currents, as well as distinct action potentials. On a molecular level, neonatal cardiomyocytes harbor a large proportion of stable, post translationally modified microtubules, contributing to their structural and contractile integrity. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Rat Cardiac Cells-Neonatal, Rat Neonatal Cardiac Cells, Neonatal Cardiomyocytes, Cardiac Cells
Species

Rat
Cat.No

ABC-TC4104
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Cardiac Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Heart
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Rat Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Neonatal rat cardiac cells serve as a versatile in vitro model for investigating cardiac development, cell-cycle regulation, electrophysiology, and drug-induced toxicity. They are frequently used to study the mechanisms of arrhythmias (e.g., sustained reentry in monolayers), calcium handling, hypertrophy, and circadian rhythm–related gene oscillations (e.g., Bmal1/Per2) under stress conditions such as hypoxia or chemotherapeutic exposure. NRVM cultures are also compatible with live-cell imaging and genetic manipulation via viral transduction, allowing precise analysis of sarcomeric dynamics, signal transduction pathways, and contractile responses.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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