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Primary Cells

Rat Dermal Fibroblasts

  • For research use only

Cat No.

ABC-TC4119
Product Type

Rat Primary Cells
Cell Type

Fibroblast
Species

Rat
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Storage

Liquid Nitrogen

Rat Dermal Fibroblasts (RDF) are derived from the dermis of normal Sprague Dawley rats.

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  • Rat Dermal Fibroblasts
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Description

Rat Dermal Fibroblasts (RDF) are primary cells isolated from the dermal layer of healthy rat skin. These spindle-shaped, adherent cells are cryopreserved at an early passage to preserve their proliferative capacity and functional integrity. Dermal fibroblasts play a vital role in extracellular matrix (ECM) synthesis, wound healing, and tissue remodeling by secreting key structural proteins such as type I and type III collagen, fibronectin, and elastin. These cells also show expression of mesenchymal marker vimentin. Rat dermal fibroblasts are commonly used in dermatological research to model inflammation, skin regeneration, and toxicological screening. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

RDF
Species

Rat
Cat.No

ABC-TC4119
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Rat Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Primary rat dermal fibroblasts are commonly used as an in vitro model for investigations of skin biology, extracellular matrix dynamics, and cellular responses relevant to wound repair. They support studies of dermal regeneration, matrix remodeling, and changes in collagen deposition associated with fibroblast activation. These cells can also be applied in laboratory evaluation of bioactive compounds, tissue scaffolds, and experimental conditions that influence fibroblast behavior and responses to inflammatory stimuli. Their responsiveness to growth factors such as TGF-β and FGF enables investigation of signaling pathways associated with matrix production and fibroblast activation in culture.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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