Rat Islets

Description

Rat Islets, also known as pancreatic islets or islets of Langerhans, are freshly isolated multicellular clusters derived from the pancreas of healthy rats. These spherical micro-organs consist primarily of insulin-producing β-cells, glucagon-secreting α-cells, somatostatin-secreting δ-cells, and pancreatic polypeptide-producing PP cells. Under optimized culture conditions, Rat Islets can partially maintain aspects of their native architecture and glucose-responsive insulin secretion in short-term in vitro culture. Islets are typically maintained as three-dimensional clusters under suspension or low-adhesion conditions, supporting short-term viability in vitro. Islet integrity and function are carefully maintained through optimized isolation and cryopreservation processes. To ensure optimal performance and insulin responsiveness, repeated freeze-thaw cycles are not recommended. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.