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RAW-264.7

Product Name

RAW-264.7

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Product Code

RAW264; RAW2647; RAW264.7; RAW-264.7; Raw 264.7; Raw264.7

Cat.No

ABC-TC0934

Species

Mouse

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

RAW-264.7 cells, originating from a BALB/c mouse tumor transformed by the Abelson leukemia virus, are a semi-adherent macrophage-like cell line highly regarded for their rapid proliferation and simple handling. With a doubling time spanning from 11 to 30 hours, these cells enter their maintenance phase within approximately 24 hours of adhering to the culture dish surface, necessitating media replenishment every 2-3 days but no later than 4 days. Typically measuring 10-20μm in diameter, RAW264.7 cells showcase essential macrophage functions, including pinocytosis and phagocytosis. As immortal cancer cells, they contribute to regulating bone remodeling without being osteoclasts. Additionally, RAW264.7 cells are easily propagated, boast high efficiency in DNA transfection, exhibit sensitivity to RNA interference, and facilitate the replication of murine noroviruses.

 

Why choose RAW-264.7 from AcceGen?

RAW-264.7 cells exhibit exceptional features, including high viability and quality, ensuring reliable experimental results. They are maintained in sterile conditions, rigorously screened for the absence of bacteria, fungi, and mycoplasma contamination. These cells are expertly incubated under optimal conditions and cryopreserved by experienced operators, guaranteeing their suitability for a wide range of research applications and maintaining rigorous quality control standards.

Disease

Leukemia

Source Organ

Blood

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The RAW-264.7 cell line serves as a valuable model for mouse macrophages in the study of cellular responses to microbes and their products, making it an essential tool for immunology and microbiology research. These cells are extensively employed in investigations related to osteoclasts, as they can differentiate into osteoclast-like cells (OCLs), enabling the exploration of underlying mechanisms and signal pathways governing precursor cell migration towards bone. Additionally, RAW-264.7 cells are a preferred choice as a transfection host due to their suitability, further enhancing their utility in various experimental contexts.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Monocyte

Growth Mode

Adherent

Product Type

Mouse Lymphocytes Cell Lines

Product Image

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