For research use only
| Cat No. | ABC-RC011Y |
| Product Type | Reporter Stable Cell Lines |
| Cell Type | Monocyte |
| Species | Mouse |
| Host Cell | Raw264.7 |
| Source Organ | Blood / Macrophage |
| Disease | Leukemia |
| Storage | Liquid Nitrogen |
Raw264.7/RFP-Luciferase Stable Cell Line by AcceGen enables dual fluorescence and bioluminescence tracking for macrophage migration and tumor studies.
Raw264.7/RFP-Luciferase Stable Cell Line is a dual-reporter macrophage model engineered from the murine Raw264.7 cell line, stably co-expressing red fluorescent protein (RFP) and luciferase. This system retains key macrophage features including phagocytosis, cytokine secretion, and CD14/F4/80 expression, while providing dual-modal tracking for in vitro and in vivo studies. RFP enables real-time fluorescence imaging, and luciferase supports sensitive bioluminescence detection for longitudinal monitoring of cell migration, tumor infiltration, and immunotherapy responses. All cells are rigorously tested and free from mycoplasma, fungi, yeast, and bacteria.
| Species | Mouse |
| Cat.No | ABC-RC011Y |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Monocyte |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Blood / Macrophage |
| Disease | Leukemia |
| Biosafety Level | 2 |
| Storage | Liquid Nitrogen |
| Product Type | Reporter Stable Cell Lines |
| Host Cell | Raw264.7 |
| Gene Info | RFP / Luciferase |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Raw264.7/RFP-Luciferase Stable Cell Line is a dual-reporter macrophage model enabling real-time tracking of immune cell dynamics through RFP fluorescence and bioluminescence imaging. This system facilitates quantitative studies of macrophage migration, tumor infiltration, and immunotherapy responses in vivo. The RFP marker allows precise cellular localization in tissues, while luciferase activity permits sensitive longitudinal monitoring of cell distribution. Particularly valuable for investigating tumor-associated macrophages, this cell line provides enhanced tissue penetration compared to GFP systems, making it ideal for studying macrophage-tumor interactions, metastatic niches, and therapeutic efficacy in preclinical models.