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Primary Cells

Rhesus Monkey PBMCs

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Peripheral Blood Mononuclear Cells (PBMCs) is any blood cell with a single nucleus. PBMCs consist of lymphocytes (T, B and NK cells), monocytes and dendritic cells. PBMCs are widely used in research fields including immunology, infectious diseases and hematological malignancies etc. Rhesus macaques are one of the most commonly utilized non-human primates in biomedical research. […]
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Species

Monkey

Cat.No

ABC-HP028X

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Monocyte

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Normal

Storage

Liquid Nitrogen

Product Type

Monkey Primary Cells

Description

Rhesus Monkey PBMCs are immune cell populations isolated from the peripheral blood of rhesus monkeys. They mainly include lymphocytes (T cells, B cells and NK cells), monocytes and a small number of dendritic cells. Morphologically, these cells exhibit a round nucleus, with variations in cell size and shape depending on the specific cell type. PBMCs serve as pivotal effectors of immune responses: T cells mediate cellular immunity, B cells secrete antibodies, NK cells play a natural killing role, and monocytes have the capacity to differentiate into macrophages or dendritic cells to participate in antigen presentation.

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Citation

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Application

  • Rhesus Monkey PBMCs can be used to analyze the activation, proliferation and functional regulation mechanisms of T cells, B cells, NK cells and monocytes. In addition, in the study of autoimmune diseases (such as rheumatoid arthritis and systemic lupus erythematosus), these cells provide an ideal platform for exploring abnormal immune responses and identify potential therapeutic targets.

Frequently Asked Questions

  • What are Peripheral Blood Mononuclear Cells (PBMCs)?

    Peripheral Blood Mononuclear Cells (PBMCs) are blood cells that have a single round nucleus. These cells include lymphocytes (such as T cells, B cells, and NK cells), monocytes, and dendritic cells. PBMCs play a crucial role in the immune system and are extensively used in research fields like immunology, infectious diseases, and hematological malignancies.

  • Why are rhesus macaques commonly used in biomedical research?

    Rhesus macaques are one of the most commonly utilized non-human primates in biomedical research due to their physiological similarities to humans. They are employed in various research areas such as immunology, neuroscience, oncology, infectious disease, and toxicology, making them valuable models for studying human diseases and developing treatments.

  • In which research fields are Rhesus Monkey PBMCs used?

    Rhesus Monkey PBMCs are widely used in research fields including immunology, where they help study immune responses; infectious diseases, where they aid in understanding pathogen-host interactions; hematological malignancies for exploring blood cancers; and other areas like neuroscience, oncology, and toxicology.

  • What cell types are included in Rhesus Monkey PBMCs?

    Rhesus Monkey PBMCs consist of several types of immune cells, including lymphocytes (T cells, B cells, and NK cells), monocytes, and dendritic cells. Each of these cell types plays a distinct role in the immune system, contributing to the body’s defense mechanisms and research applications.

  • How can researchers utilize Rhesus Monkey PBMCs in their studies?

    Researchers can utilize Rhesus Monkey PBMCs to investigate various aspects of the immune system, study the effects of infectious agents, develop and test new therapies for hematological malignancies, and explore the physiological responses in fields such as neuroscience, oncology, and toxicology. These cells provide a valuable tool for understanding disease mechanisms and evaluating potential treatments.

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