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Product Code | RT112-84; RT-112/84; RT11284 |
Species | Human |
Cat.No | ABC-TC0999 |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Epithelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Bladder |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Human Bladder Cancer Cell Lines |
RT112/84 is a human bladder transitional cell carcinoma (TCC) cell line established in 1973 from a primary tumor of an untreated female patient with bladder cancer. The cells exhibit epithelial-like morphology and adherent growth properties, with a reported doubling time of approximately 23–35 hours. RT112/84 is tumorigenic in vivo, capable of forming subcutaneous tumors in nude mice. Its applications focus on investigating bladder cancer pathogenesis, particularly in the context of tumor progression, drug resistance mechanisms, and therapeutic development.
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RT-112/84 cells offers valuable applications in cancer research, particularly in exploring cancer cell mechanisms of cancer cell invasion and metastasis. They are frequently used in tumorigenicity studies and are instrumental in evaluating the efficacy of anticancer agents. The cell line has been applied in cytotoxicity assays involving compounds such as lipoic acid and calcium hydroxycitrate, providing insights into potential therapeutic interventions. Its reproducible growth and tumor-forming capabilities make it a valuable platform for drug screening and mechanistic studies in urothelial carcinoma.