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Tumor Cell Lines

RT-112/84

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Human bladder carcinoma epithelial. A slow growing tumour which does not form colonies in soft agar. Tumorigenic in nude mice, RT1112/84 cells possess a low plating efficiency requiring 400 cells/dish to form any colonies.
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Product Code

RT112-84; RT-112/84; RT11284

Species

Human

Cat.No

ABC-TC0999

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bladder

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Bladder Cancer Cell Lines

Description

RT-112/84RT112/84 is a human bladder transitional cell carcinoma (TCC) cell line established in 1973 from a primary tumor of an untreated female patient with bladder cancer. The cells exhibit epithelial-like morphology and adherent growth properties, with a reported doubling time of approximately 23–35 hours. RT112/84 is tumorigenic in vivo, capable of forming subcutaneous tumors in nude mice. Its applications focus on investigating bladder cancer pathogenesis, particularly in the context of tumor progression, drug resistance mechanisms, and therapeutic development.

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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • RT-112/84 cells offers valuable applications in cancer research, particularly in exploring cancer cell mechanisms of cancer cell invasion and metastasis. They are frequently used in tumorigenicity studies and are instrumental in evaluating the efficacy of anticancer agents. The cell line has been applied in cytotoxicity assays involving compounds such as lipoic acid and calcium hydroxycitrate, providing insights into potential therapeutic interventions. Its reproducible growth and tumor-forming capabilities make it a valuable platform for drug screening and mechanistic studies in urothelial carcinoma.

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