For research use only
| Cat No. | ABC-TC1190 |
| Product Type | Human Bladder Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Colon |
| Product Code | SW-780; SW780 |
SW780 human bladder cancer cells from 80-year-old patient show epithelial morphology, adherent growth, tumorigenic, form tumors in nude mice models.
SW780 is a human bladder cancer cell line originally derived from a stage I transitional cell carcinoma of the bladder from an 80-year-old patient who had been treated with Thiotepa chemotherapy prior to surgery in 1974. These cells grow adherently in vitro, exhibiting polygonal epithelial morphology, and can be continuously passaged. SW780 cells express epithelial markers such as cytokeratins and uroplakin, consistent with their urothelial origin. They harbor tumor-associated mutations including TP53 and FGFR3, reflecting key molecular alterations in bladder cancer. The cells retain some differentiation characteristics of normal urothelium and produce extracellular matrix components. SW780 serves as a widely used in vitro model for investigating bladder cancer biology, tumor progression, and therapeutic responses.
| Product Code | SW-780; SW780 |
| Species | Human |
| Cat.No | ABC-TC1190 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Colon |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Bladder Cancer Cell Lines |
SW 780 is a human bladder cancer cell line widely used in bladder cancer research. It is particularly useful in establishing CDX (cell line-derived xenograft) mouse models to evaluate treatment efficacy. These models enable detailed assessment of pharmaceutical agents in modulating tumor growth, supporting the development of novel and targeted therapies for bladder cancer management
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