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TF-1

Product Name

TF-1

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Product Code

TF1; MFD-1

Cat.No

ABC-TC1229

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The TF-1 cell line has been established by T. Kitamura in October 1987 from a heparinized bone marrow aspiration sample from a 35 year old Japanese male with severe pancytopenia. They dont respond to interleukin 5 (IL-5), but to a variety of other lymphokines and cytokines such as interleukin 1 (IL-1), interleukin 4 (IL-4), interleukin 6 (IL-6), interleukin 9 (IL-9), Interleukin 11 (IL-11), interleukin 13 (IL-13), stem cell factor (SCF), leukemia inhibitory factor (LIF) and nerve growth factor (NGF). The morphological and cytochemical features, and the constitutive expression of globin genes, indicate the commitment of the cells to the erythroid lineage. TPA induces a dramatic differentiation into macrophage-like cells; Hemin and delta-aminolevulinic acid induce hemoglobin synthesis.

Source Organ

Blood

Recommended Medium And Supplement
Citation Guide

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Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Growth Mode

Suspension

Product Type

Human Lymphoma Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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