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Tumor Cell Lines

KG-1

  • For research use only

Cat No.

ABC-TC0498

Product Type

Human Leukemia Cell Lines

Cell Type

Myeloblast-like

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Product Code

KG1

KG-1 cell line is a human acute myelogenous leukemia model used for hematopoietic, cancer biology, and preclinical therapeutic testing research.

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Description

KG-1 is a human acute myelogenous leukemia (AML) cell line derived from a bone marrow aspirate of a 59-year-old Caucasian male patient originally diagnosed with erythroleukemia that subsequently progressed to acute myelogenous leukemia, representing an early myeloid progenitor phenotype. The cells grow as suspension-cultured myeloblast-like cells with characteristic morphology and exhibit responsiveness to colony-stimulating factors typical of myeloid blasts. Molecular cytogenetic analyses have demonstrated a complex, pseudodiploid karyotype with multiple structural rearrangements, consistent with genetic instability observed in AML and useful for cytogenetic authentication. KG-1 cells have also been shown to differentiate toward macrophage-like cells under defined cytokine conditions in vitro. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

KG1

Species

Human

Cat.No

ABC-TC0498

Product Category

Tumor Cell Lines

Size/Quantity

1 vial

Cell Type

Myeloblast-like

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Leukemia Cell Lines

Application

  • KG-1 is widely used as an in vitro model for human acute myelogenous leukemia research, including studies of myeloid differentiation, leukemogenesis, and hematopoietic signaling pathways. The line supports investigation of cytokine and growth factor responses, gene regulation underlying progenitor cell behavior, and preclinical evaluation of differentiation-inducing agents, signaling inhibitors, and therapeutic strategies targeting AML biology.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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