For research use only
| Cat No. | ABC-TC0498 |
| Product Type | Human Leukemia Cell Lines |
| Cell Type | Myeloblast-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Product Code | KG1 |
KG-1 cell line is a human acute myelogenous leukemia model used for hematopoietic, cancer biology, and preclinical therapeutic testing research.
KG-1 is a human acute myelogenous leukemia (AML) cell line derived from a bone marrow aspirate of a 59-year-old Caucasian male patient originally diagnosed with erythroleukemia that subsequently progressed to acute myelogenous leukemia, representing an early myeloid progenitor phenotype. The cells grow as suspension-cultured myeloblast-like cells with characteristic morphology and exhibit responsiveness to colony-stimulating factors typical of myeloid blasts. Molecular cytogenetic analyses have demonstrated a complex, pseudodiploid karyotype with multiple structural rearrangements, consistent with genetic instability observed in AML and useful for cytogenetic authentication. KG-1 cells have also been shown to differentiate toward macrophage-like cells under defined cytokine conditions in vitro. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | KG1 |
| Species | Human |
| Cat.No | ABC-TC0498 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Myeloblast-like |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone Marrow |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Leukemia Cell Lines |
KG-1 is widely used as an in vitro model for human acute myelogenous leukemia research, including studies of myeloid differentiation, leukemogenesis, and hematopoietic signaling pathways. The line supports investigation of cytokine and growth factor responses, gene regulation underlying progenitor cell behavior, and preclinical evaluation of differentiation-inducing agents, signaling inhibitors, and therapeutic strategies targeting AML biology.
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