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Xpress™ Human CD47 Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CD47 Over-expressing Cell Line (293T)
Species

Human
Cat.No

ABC-X0186C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Human CD47 overexpression cell line is generated by stable integration of exogenous human CD47 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD47 is a ubiquitously expressed transmembrane protein known for its role as a “don’t eat me” signal through interaction with SIRPα on phagocytic cells. It is overexpressed in many tumors and implicated in immune evasion. Targeting CD47 is a promising strategy in cancer immunotherapy.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Human CD47 Overexpression Cell Line is ideal for studying innate immune evasion, macrophage-mediated phagocytosis, and development of anti-CD47 checkpoint inhibitors. It enables screening of therapeutic antibodies, small molecules, and bispecific fusion proteins.

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