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Transfected Stable Cell Lines

Xpress™ Human CD47 Over-expressing Cell Line (293T)

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  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Species

Human

Cat.No

ABC-X0186C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Kidney

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

293T

Description

Human CD47 overexpression cell line is generated by stable integration of exogenous human CD47 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CD47 is a ubiquitously expressed transmembrane protein known for its role as a “don’t eat me” signal through interaction with SIRPα on phagocytic cells. It is overexpressed in many tumors and implicated in immune evasion. Targeting CD47 is a promising strategy in cancer immunotherapy.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The Human CD47 Overexpression Cell Line is ideal for studying innate immune evasion, macrophage-mediated phagocytosis, and development of anti-CD47 checkpoint inhibitors. It enables screening of therapeutic antibodies, small molecules, and bispecific fusion proteins.

Inquiring Xpress™ Human CD47 Over-expressing Cell Line (293T)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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