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Xpress™ Human LOXL2 Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human LOXL2 Over-expressing Cell Line (293T)
Species

Human
Cat.No

ABC-X0201C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Human LOXL2 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney 293T parental cell line based on customers’ requirement. LOXL2 293T overexpression cell line is generated by stable integration of exogenous human LOXL2 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT‑PCR.
Target
The LOXL2 gene encodes lysyl oxidase‑like 2, an extracellular enzyme that cross‑links collagen and elastin, promoting matrix stiffening, epithelial–mesenchymal transition (EMT), fibrosis, and metastatic niche formation in breast, liver, and pancreatic cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The LOXL2 293T Overexpression Cell Line is a powerful tool for investigating ECM remodeling, EMT induction, and anti‑fibrotic or antimetastatic drug discovery targeting LOXL2 catalytic activity or protein–protein interactions.

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