For research use only
| Cat No. | ABC-X0201C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The Xpress™ Human LOXL2 Overexpression Cell Line (293T) facilitates research on tumor invasion, metastasis, and ECM remodeling in cancer models.
Human LOXL2 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney 293T parental cell line based on customers’ requirement. LOXL2 293T overexpression cell line is generated by stable integration of exogenous human LOXL2 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT‑PCR.
Target
The LOXL2 gene encodes lysyl oxidase‑like 2, an extracellular enzyme that cross‑links collagen and elastin, promoting matrix stiffening, epithelial–mesenchymal transition (EMT), fibrosis, and metastatic niche formation in breast, liver, and pancreatic cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0201C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The LOXL2 293T Overexpression Cell Line is a powerful tool for investigating ECM remodeling, EMT induction, and anti‑fibrotic or antimetastatic drug discovery targeting LOXL2 catalytic activity or protein–protein interactions.