For research use only
| Cat No. | ABC-X0185C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
NCR3 overexpression cell lines validated by qRT-PCR assist in studying NK cell activation and anti-tumor immunity, catering to diverse research needs.
Human NCR3 overexpression cell line is generated by stable integration of exogenous human NCR3 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
NCR3 (natural cytotoxicity triggering receptor 3), also known as NKp30, is a member of the natural cytotoxicity receptor family. It plays a critical role in NK cell-mediated cytotoxicity and immune surveillance against tumors and viral infections. NCR3 expression is primarily restricted to natural killer cells.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0185C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Human NCR3 Overexpression Cell Line serves as a valuable platform for studying NK cell activation, immune checkpoint pathways, and anti-tumor immunity. It supports screening of immunotherapies and monoclonal antibodies targeting NK cell-mediated cytotoxicity.