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| Species | Mouse- C3H |
| Cat.No | ABC-TC058S |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Embryo Cell Lines |
The 10T1/2 cell line, also known as C3H/10T1/2, Clone 8, is derived from C3H mouse embryo cells and displays fibroblast-like morphology. Notably, it exhibits multipotential characteristics, capable of differentiating into three mesodermal stem cell lineages upon treatment with 5-azacytidine. These cells display a heightened sensitivity to post-confluence inhibition of cell division, yet they do not elicit tumor formation in syngeneic mice. Importantly, they exhibit no spontaneous transformation and lack endogenous transforming murine leukemia or sarcoma viruses. Furthermore, the 10T1/2 cells exhibit contact sensitivity.
Why choose 10T1/2 from AcceGen?
The 10T1/2 cell line from AcceGen is characterized by its exceptional quality and high viability, cultivated under optimal incubation conditions. These cells are provided in a sterile state and rigorously screened to ensure they are free from contaminants, including bacteria, yeast, fungi, mycoplasma, and major pathogens such as HIV, HBV, and HCV, guaranteeing the reliability of the cell line for research purposes.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The 10T1/2 cell line serves as a valuable in vitro model for the molecular genetic analysis of mesodermal determination and differentiation. This cell line presents a distinctive platform for investigating the intricate molecular mechanisms that govern the developmental determination of vertebrate stem cell lineages and their subsequent differentiation. Researchers can utilize 10T1/2 cells to gain insights into the genetic regulation of these critical processes, making it a valuable tool for advancing our understanding of mesodermal development.
