Primary Cells

B6129SF2/J Mouse Bone Marrow Neutrophils

  • For research use only

Cat No.

ABC-TC3039

Product Type

Mouse Primary Cells

Cell Type

Neutrophil

Species

B6129SF2/J Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Normal

Storage

Liquid Nitrogen

Utilize B6129SF2/J Mouse Bone Marrow Neutrophils to study innate immune responses, neutrophil activation, and inflammation in murine disease models.

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Description

B6129SF2/J Mouse Bone Marrow Neutrophils are isolated from the bone marrow of B6129SF2/J mice and represent a defined subset of mouse bone marrow immune cells. These cells exhibit a circular morphology and grow in suspension. These terminally differentiated granulocytes play a central role in innate immunity and are characterized by high expression of Ly6G and CD11b, with a multilobed nuclear morphology. Bone marrow-derived neutrophils exhibit robust chemotaxis, reactive oxygen species (ROS) production, and phagocytic activity. Due to their short lifespan and terminal differentiation status, they are not suitable for passaging and should be used immediately after thawing. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

B6129SF2/J Mouse Bone Marrow Neutrophils, B6129SF2/J BMNs, B6-129F2 BM Neutrophils, B6129 BM-PMNs

Species

B6129SF2/J Mouse

Cat.No

ABC-TC3039

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Neutrophil

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • These neutrophils are ideal for in vitro assays investigating inflammation, infection, and immune cell signaling. They exhibit rapid chemotaxis in response to inflammatory stimuli and demonstrate high phagocytic activity against pathogens and debris. They are commonly used to study neutrophil extracellular trap (NET) formation, cytokine responses, and interactions with pathogens or tumor cells, supporting research into autoimmune and inflammatory diseases.These cells generate abundant reactive oxygen species (ROS) upon activation and serve as a reliable model for studying innate immune cell recruitment and effector functions. Their short lifespan closely mimics physiological neutrophil dynamics in vivo.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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