Primary Cells

B6129SF2/J Mouse Lung Endothelial Cells

  • For research use only

Cat No.

ABC-TC3049

Product Type

Mouse Primary Cells

Cell Type

Endothelial

Species

B6129SF2/J Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lung

Disease

Normal

Storage

Liquid Nitrogen

Mouse primary lung endothelial cells (MPLUECs) are isolated from tissue of pathogen-free laboratory mice.

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Description

B6129SF2/J Mouse Lung Endothelial Cells are isolated from lung tissue of B6129SF2/J hybrid mice and represent a key component of the pulmonary vasculature. These primary endothelial cells form a confluent monolayer with a cobblestone-like morphology under standard culture conditions and express typical markers such as CD31 and VE-cadherin. Cells are non-tumorigenic and should be used at early passages with limited freeze-thaw cycles to maintain physiological relevance. They are essential for maintaining vascular barrier integrity, mediating immune cell trafficking, and regulating gas exchange and inflammation in the lung. Lung endothelial dysfunction has been implicated in acute lung injury, pulmonary hypertension, and sepsis-induced vascular leakage. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

B6129SF2/J Mouse Lung Endothelial Cells, B6129SF2/J LEC, B6-129F2 Lung ECs, B6129 Pulmonary ECs

Species

B6129SF2/J Mouse

Cat.No

ABC-TC3049

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Endothelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lung

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • B6129SF2/J Mouse Lung Endothelial Cells serve as a valuable in vitro model for investigating B6129SF2/J mouse lung endothelial physiology, including endothelial barrier regulation, leukocyte adhesion, and the molecular basis of pulmonary vascular diseases. They are widely used in inflammation, hypoxia, and permeability assays to investigate pathologies such as acute respiratory distress syndrome and pulmonary fibrosis. These cells enable detailed analysis of vascular permeability changes, cytokine-mediated signaling, and endothelial responses to hypoxic stress, supporting drug screening and mechanistic studies of pulmonary vascular dysfunction.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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