BALB/c Mouse Bone Marrow Leukocytes

Description

BALB/c Mouse Bone Marrow Leukocytes are isolated from the bone marrow of BALB/c mice and serve as representative bone marrow leukocyte models in BALB/c mice. This heterogeneous population includes granulocytes, lymphocytes, monocytes, and progenitor cells, with most cells exhibiting suspension growth . Functionally, these leukocytes mediate critical immune responses such as phagocytosis, antigen presentation, and cytokine production. Phenotypically, they express myeloid markers like CD11b and Ly6G, with leukemia models showing elevated nm23-M1 gene expression linked to disease progression. These primary cells are cryopreserved immediately post-isolation and cannot be passaged in vitro. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.