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Primary Cells

BALB/c Mouse Bone Marrow Macrophages

  • For research use only

Cat No.

ABC-TC3058
Product Type

Mouse Primary Cells
Cell Type

Macrophage
Species

BALB/c Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Normal
Storage

Liquid Nitrogen

Mouse bone marrow macrophages (MPBMMACs) are derived from the tibias and femurs of pathogen-free laboratory adult mice.

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  • BALB/c Mouse Bone Marrow Macrophages
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | BALB/c Mouse Bone Marrow Macrophages

Description

BALB/c Mouse Bone Marrow Macrophages (BMDMs) are isolated from pathogen-free adult BALB/c mice. Functionally, they exhibit robust phagocytosis, immune surveillance, and cytokine secretion (e.g., TNF-α, IL-6), playing critical roles in inflammation, infection response, and tissue homeostasis. They consistently express macrophage surface markers F4/80 and CD11b, but show variable MHC-II expression during culture, making them a relevant model for BALB/c marrow macrophage gene expression studies. These cells are terminally differentiated and non-proliferative; repeated freeze-thaw cycles must be avoided. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

BALB/c Mouse Bone Marrow Macrophages, BALB/c BMM, BALB BM Macrophages, BALB BM-Macs
Species

BALB/c Mouse
Cat.No

ABC-TC3058
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Macrophage
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • BALB/c Mouse Bone Marrow Macrophages serve as versatile tools for studying innate immunity, including cytokine responses (e.g., LPS/IFNγ-induced M1 or IL-4-driven M2 polarization), pathogen-macrophage interactions, and strain-specific mechanisms of oxidative stress and lysosomal activity, offering insights for disease modeling and therapeutic development. They also facilitate exploration of macrophage metabolism and effector functions under inflammatory and tissue repair conditions, enabling drug screening and immunomodulatory research.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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