For research use only
| Cat No. | ABL-TC0104 |
| Product Type | Human Uterine Cancer Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Placenta |
| Disease | Choriocarcinoma |
| Product Code | BEWO; Be Wo; Be-Wo |
BeWo is a human choriocarcinoma line with trophoblast markers and syncytialization ability, modeling placental barrier and hormonal functions.
BeWo is a cell line exhibiting epithelial morphology that was isolated from the placenta of a patient with choriocarcinoma. The cells exhibit an epithelial-like morphology and grow as monolayer under adherent conditions. Characterized by a hypotetraploid stemline karyotype, with a modal chromosome number of 86, and a range of 71-178 chromosomes. BeWo cells express key trophoblast-specific markers, including human chorionic gonadotropin (hCG), placental lactogen, and various estrogen isoforms. They also displays tumorigenic potential and are permissive to poliovirus type 3 and vesicular stomatitis virus. Its unique capacity for syncytialization makes it particularly valuable for modeling placental barrier functions and hormonal regulation.
| Product Code | BEWO; Be Wo; Be-Wo |
| Species | Human |
| Cat.No | ABL-TC0104 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Placenta |
| Disease | Choriocarcinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
BeWo cells are a widely used for studying human placental development, particularly the syncytialization of trophoblast, a critical yet poorly understood process to investigate. Their abiity to undergo cell-cell fusion enables detailed exploration of placental villous trophoblast differentiation, hormonal regulation, and barrier function formation during early pregnancy. BeWo cells are instrumental in studying the molecular mechanisms behind placental hormone secretion, nutrient transport, and virus-host interactions, and are often used to evaluate the toxicological and pharmacokinetic effects of compounds crossing the placental barrier.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
