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| Product Code | C-4II; C4 II; C4II |
| Species | Human |
| Cat.No | ABC-TC0097 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervical Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
The C-4 II cell line is derived from a 41-year-old Caucasian female with cervical carcinoma. These cells predominantly form monolayered, epithelial colonies with distinct hemicysts, commonly seen in transporting epithelia. They respond to crowded conditions by separating and shedding.
Even after prolonged periods of cultivation, the cells maintain their basal cell differentiation properties and demonstrate G6PD type B. Notably, C-4 II cells harbor human papilloma virus 18 (HPV-18) DNA sequences and actively express HPV-18 RNA. For subculturing, it is recommended to split sub-confluent cultures (70-80%) at a ratio ranging from 1:4 to 1:10.
Why choose C-4 II from AcceGen?
AcceGen’s C-4 II is an excellent choice for superior quality and viability. The cells are incubated under sterile and optimal conditions, cryopreserved using advanced techniques, and undergo rigorous quality control testing.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
The C-4 II cell line finds valuable applications in various fields of research. In 3D cell culture, these cells offer an excellent model to study cell behavior and tissue formation in a more physiologically relevant environment. In cancer research, C-4 II cells provide insights into cervical carcinoma progression and potential therapeutic targets. Additionally, in infectious disease research, their interaction with human papilloma virus 18 (HPV-18) offers valuable insights into viral infections and possible antiviral strategies. Furthermore, in sexually transmitted disease research, studying HPV-18’s impact on these cells helps understand the pathogenesis and transmission of the virus, aiding in the development of preventive measures and treatments.
