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Primary Cells

C57 Mouse Cortex Neurons

  • For research use only

Cat No.

ABC-TC3919
Product Type

Mouse Primary Cells
Cell Type

Neuron
Species

C57 Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Brain
Disease

Normal
Storage

Liquid Nitrogen

Mouse Brain Cortex Neurons are isolated from Mouse C57 black brain (E14, 15) or Mouse CD1 brain (E14,15).

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  • C57 Mouse Cortex Neurons
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57 Mouse Cortex Neurons

Description

C57 Mouse Cortex Neurons are isolated from the cerebral cortex of C57BL/6 mice. As primary neuronal cells, they are terminally differentiated and display a typical pyramidal morphology with complex dendritic spines and axonal projections essential for neural circuit formation. These cells grow in an adherent manner on coated surfaces. Functionally, cortex neurons mediate sensory perception, motor control, and cognitive processes. They are associated with neurological disorders like Parkinson’s disease and stroke. The cells express neuronal marker β-III tubulin, while karyotype analysis shows normal diploidy. These cells lack proliferative capacity in vitro. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

C57 Mouse Cortex Neurons, C57BL/6 Cortical Neurons, C57 Cortex Neurons, Murine C57 Cortical Neurons
Species

C57 Mouse
Cat.No

ABC-TC3919
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Neuron
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Brain
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • C57 Mouse Cortex Neurons serve as an in vitro model to study mechanisms underlying neurodegenerative, neurodevelopmental, and injury-related neurological disorders, including Parkinson’s disease, stroke, and autism spectrum disorders. For example, by investigating their survival, dendritic arborization, and response to neurotoxins or excitotoxic stress, researchers can explore molecular pathways underlying cortical dysfunction. The cells are particularly valuable for electrophysiological studies, high-content screening of neuroactive compounds, and modeling cortical network abnormalities associated with neurodevelopmental disorders.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What is C57 Mouse Cortex Neurons?

    C57 Mouse Cortex Neurons are neurons isolated from the cortex of C57BL/6 mice, characterized by their ability to maintain electrophysiological properties and morphological features in vitro, making them valuable for detailed cellular and molecular studies.

  • Application of C57 Mouse Cortex Neurons

    C57 Mouse Cortex Neurons are utilized in experiments to study brain function, neurodevelopment, and neurological diseases. These neurons are essential for research in synaptic plasticity, neuropharmacology, electrophysiology, and neurotoxicity. They enable scientists to investigate the mechanisms underlying learning and memory, evaluate the effects of drugs on neuronal activity, and explore the cellular responses to toxic insults. Additionally, they provide valuable insights into the pathophysiology of neurodegenerative diseases like Alzheimer’s and Parkinson’s, aiding in the development of potential therapeutic interventions.

  • What is the growth and morphology of C57 Mouse Cortex Neurons?

    Medium: ABM-TM3919 C57 Mouse Cortex Neurons Medium Kit

    C57 Mouse Cortex Neurons exhibit a complex morphology with extensive dendritic and axonal arborization, typical of cortical neurons. They grow in vitro on poly-D-lysine or laminin-coated surfaces, requiring a neurobasal medium supplemented with B27, glutamine, and growth factors. These neurons typically form synaptic connections and display spontaneous electrical activity, making them ideal for studying neuronal connectivity and function. Optimal growth conditions include maintaining at 37oC in a humidified atmosphere with 5% CO2.

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