C57BL/10J Mouse Heart Fibroblasts

Description

C57BL/10J Mouse Heart Fibroblasts are the main cell type in the cardiac interstitium. They originate from the embryonic mesoderm and play a key role in cardiac development and homeostasis maintenance. Morphologically, these cells are spindle-shaped or irregularly star-shaped, with obvious cytoplasmic processes. These cells express extracellular matrix (ECM) components such as fibronectin. Functionally, these cells maintain the structural integrity of the heart by secreting ECM and participate in scar formation through proliferation and phenotypic transformation (such as myofibroblast differentiation) during injury repair. Additionally, studies of the C57BL/10J cardiac extracellular matrix have provided insights into heart fibroblast gene expression, highlighting their regulatory roles in tissue remodeling. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.