Primary Cells

C57BL/6 Mouse Aortic Smooth Muscle Cells

  • For research use only

Cat No.

ABC-TC3164

Product Type

Mouse Primary Cells

Cell Type

Smooth Muscle Cell

Species

C57BL/6 Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Aortic

Disease

Normal

Storage

Liquid Nitrogen

Mouse Aortic Vascular Smooth Muscle Cells from AcceGen are isolated from tissue of pathogen-free laboratory mice.

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Description

C57BL/6 Mouse Aortic Smooth Muscle Cells are isolated from the aortic tissue of C57BL/6 mice and represent the main cell type of the tunica media in the vascular wall. These cells are usually spindle-shaped in morphology, grow adherently, and form a monolayer cell structure. They express smooth muscle cell marker α-smooth muscle actin (α-SMA). Their functions include regulating vascular tension through contraction-relaxation, participating in the remodeling process of the vascular wall, and maintaining the integrity of the vascular structure by secreting extracellular matrix (ECM) components such as collagen (type I/III) and elastin. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

C57BL/6 Mouse Aortic Smooth Muscle Cells,Mouse Aortic Smooth Muscle Cells,SMCs,C57BL/6 MASMCs

Species

C57BL/6 Mouse

Cat.No

ABC-TC3164

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Smooth Muscle Cell

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Aortic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • C57BL/6 Mouse Aortic Smooth Muscle Cells can be utilized to investigate the phenotypic transformation mechanisms of vascular smooth muscle cells (VSMCs), including the transition from the contractile to the synthetic phenotype, a process closely associated with vascular pathological remodeling. These cells are also commonly employed to evaluate the inhibitory effects of drugs (such as statins or TGF-β inhibitors) on the proliferation of smooth muscle cells.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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