C57BL/6 Mouse Artery Smooth Muscle Cells

Description

C57BL/6 Mouse Artery Smooth Muscle Cells are primary cells isolated from the thoracic aorta, abdominal aorta, and mesenteric arteries of pathogen-free laboratory mice, serving as a classic C57BL/6 mouse model for studying vascular smooth muscle function and arterial health. These cells can regulate vascular tone through contraction and relaxation, mediate extracellular matrix remodeling, and secrete inflammatory cytokines. They are implicated in vascular pathologies including atherosclerosis, hypertension-induced medial hypertrophy, and neointimal hyperplasia following vascular injury. In vitro, these primary cells exhibit limited proliferation and passage capacity. Repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.