C57BL/6 Mouse Bone Marrow Neutrophils

Description

C57BL/6 Mouse Bone Marrow Neutrophils are primary cells isolated from the tibias and femurs of pathogen-free laboratory mice and serve as a reliable model for C57BL/6 hematopoietic cell analysis. They primarily reside in the hematopoietic compartment of the bone marrow cavity in long and flat bones. Following primary culture, these cells are cryopreserved. These primary innate immune cells rapidly migrate to infection sites, eliminate pathogens through phagocytosis, reactive oxygen species (ROS) production, and neutrophil extracellular traps (NETs) formation (DNA traps). These neutrophils also modulate inflammatory responses via cytokine secretion (TNF-α, IL-1β), and contribute to tissue repair. They express CD11b. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.