+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Primary Cells

C57BL/6 Mouse Liver Cells

  • For research use only

Cat No.

ABC-TC3205
Product Type

Mouse Primary Cells
Cell Type

Liver Cell
Species

C57BL/6 Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

Liquid Nitrogen

C57BL/6 mouse liver cells include hepatocytes, Kupffer and stellate cells, vital for liver injury and immune response modeling in vitro and ex vivo assays.

Product Image
  • C57BL/6 Mouse Liver Cells
Get a Quote
Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57BL/6 Mouse Liver Cells

Description

C57BL/6 Mouse Liver Cells are primary cells isolated from the liver tissue of pathogen-free C57BL/6 mice. This heterogeneous population was characterized using immunocytochemical methods, including parenchymal hepatocytes, Kupffer cells (F4/80⁺ macrophages), hepatic stellate cells (GFAP⁺), and endothelial cells (CD34⁺). Functionally, Kupffer cells perform phagocytosis and immune surveillance, clearing pathogens and cellular debris, whereas stellate cells regulate extracellular matrix remodeling. These cells are implicated in liver injury models, including non-alcoholic fatty liver disease (NAFLD) and toxin-induced hepatitis through cytokine secretion (e.g., TNF-α, IL-6) and inflammatory responses. Due to limited expansion capacity, repeated freezing/thawing cycles should be avoided to maintain viability. This primary cell system provides a physiologically relevant platform for studying hepatic pathophysiology without genetic background variability .

Product Code

MLIC
Species

C57BL/6 Mouse
Cat.No

ABC-TC3205
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Liver Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Mouse liver cells, especially hepatocytes, serve as a crucial predictive model in drug development. They effectively simulate drug interactions within the liver, supporting preclinical in vitro studies on drug metabolism and pharmacokinetics. These cells are widely used to evaluate drug clearance, metabolic pathways, cellular uptake, hepatotoxicity, and drug-drug interactions. Sharing similar drug-metabolizing enzymes with human hepatocytes, particularly in biotransformation processes, mouse liver cells provide a reliable platform to predict human drug responses. Additionally, cryopreserved mouse liver cells offer a cost-effective and practical alternative to in vivo studies, available in various formats to meet diverse experimental needs, thereby accelerating drug discovery and development.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

  • Online Inquiry
  • Product Reviews

Inquiring C57BL/6 Mouse Liver Cells

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button