C57BL/6 Mouse Pulmonary Artery Fibroblasts

Description

C57BL/6 Mouse Pulmonary Artery Fibroblasts, also referred to as C57BL/6 pulmonary artery fibroblasts and derived from Murine pulmonary artery adventitial cells, are isolated from the adventitial layer of pulmonary arteries in C57BL/6 mice. These fibroblasts contribute to extracellular matrix production, vascular remodeling, and fibrotic responses under both normal and disease conditions. Pulmonary artery fibroblasts are involved in processes such as fibrosis, inflammation, and vascular stiffening, and are commonly used in studies of pulmonary hypertension and chronic lung disease. They express characteristic fibroblast markers such as vimentin. Repeated freeze-thaw cycles should be avoided in vitro to preserve cell viability and functional phenotype. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.