C57BL/6 Mouse Renal Glomerular Endothelial Cells

Description

C57BL/6 Mouse Renal Glomerular Endothelial Cells are derived from the glomerular capillary loops of kidney tissue in C57BL/6 mouse. These specialized endothelial cells form a critical component of the glomerular filtration barrier and regulate capillary permeability. These murine GEC primary cells exhibit typical cobblestone endothelial morphology and express key endothelial markers such as CD31, VE-cadherin, and von Willebrand factor (vWF). Glomerular endothelial cells are essential for maintaining renal vascular homeostasis and responding to inflammatory and metabolic insults. Studies have shown their involvement in diabetic nephropathy, glomerulonephritis, and hypertensive kidney disease. Mouse glomerular endothelial cells serve as a valuable model for studying renal microvascular function and disease mechanisms. Avoid repeated freeze-thaw cycles in vitro to maintain cell viability and function. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.