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Primary Cells

Canine Bone Marrow Mononuclear Cells

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Canines are often used as a non-rodent model for studying the efficacy and safety of newly developed drugs and chemicals. This is mostly due to the similarities in their anatomical morphology and physiology compared to humans. Bone Marrow Mononuclear Cells (BMMCs) are a heterogenous mixture of cells isolated from bone marrow and is especially rich […]
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Home | Primary Cells | Animal Primary Cells | Canine Primary Cells | Canine Bone Marrow Mononuclear Cells
Species

Canine
Cat.No

ABC-SC0134T
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Monocyte
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Bone Marrow
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Canine Primary Cells

Description

Canine bone marrow mononuclear cells are derived from the bone marrow of beagle dog. When checking if the newly developed drugs are efficient and safe, canines are quite useful as a non-rodent model due to their similar morphology and physiology in anatomy compared to humans. Bone marrow mononuclear cells(BMMCs) are a heterogenous mixture, consisting of several types of cells, including monocytes, lymphocytes, and hematopoietic stem and progenitor cells. Among these bone marrow mononuclear cells, hematopoietic stem cell is the major cell population.

Canine Bone Marrow Mononuclear CellsWhy choose Canine Bone Marrow Mononuclear Cells from AcceGen?

AcceGen supports a stable bone marrow mononuclear cell product by isolation from bone marrow using density gradient centrifugation. All cell lots are cryopreserved for the best quality and highest viability. With a rigorous regulation of quality control, all cells are negative for HIV-1, HBV, and HCV.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • FOR RESEARCH USE ONLY

  • In dogs, the transplantation of autologous bone marrow mononuclear cells was used as a treatment for ununited anconeal process. Results showed that newly formed bone tissue was observed at the site of implantation. Moreover, a clinical trial showed that the transplantation of bone marrow mononuclear cells significantly increased the recovery rate of an acute spinal cord injury of the dog. In humans, bone marrow mononuclear cells transplantation has been widely accepted as a safe and reliable treatment for leukemia. Furthermore, canine bone marrow mononuclear cells can be used to study the secretion of growth factors and cytokines due to their regenerative potential.

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