CD57 Mouse Cerebellar Granule Cells

Description

CD57 Mouse Cerebellar Granule Cells are isolated from the cerebellar region of C57BL/6 mice. As one of the most abundant neuronal populations in the brain, cerebellar granule cells (CGCs) play a crucial role in synaptic transmission and cerebellar circuit development. In culture, CGCs typically form dense clusters or small aggregates. These primary neurons are carefully harvested and cryopreserved immediately after isolation to preserve their physiological properties. CGCs exhibit a round to oval morphology. These cells express key neuronal markers such as β-tubulin III and MAP2, and are widely used in research focusing on neuronal differentiation, neurotoxicity, and synaptic plasticity. CGCs are particularly relevant in modeling neurodevelopmental disorders and cerebellar ataxias. It is recommended to avoid repeated freeze-thaw cycles, and these cells should not be subcultured. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.