For research use only
| Cat No. | ABC-TC3328 |
| Product Type | Mouse Primary Cells |
| Cell Type | Neuron |
| Species | CD57 Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The tissue of the central nervous system is made up of two classes of cells that may be broadly categorized as neurons and glia.
CD57 Mouse Hippocampal Neurons are isolated from the hippocampal region of C57BL/6 mice. These primary neurons are derived from the central nervous system and exhibit typical neuronal morphology, including prominent soma and extended neurites. These neurons do not undergo passaging and are typically cryopreserved shortly after initial culture. Hippocampal neurons play a vital role in synaptic plasticity, learning, and memory. These primary neurons are non-passaged and used at early stages after isolation. They are frequently used in studies investigating excitotoxicity, neurodegeneration, synaptogenesis, and neurotransmission. C57BL/6 derived hippocampal neurons are also instrumental in studying neurological disorders such as Alzheimer’s disease, epilepsy, and ischemic brain injury. These neurons express high levels of NeuN and MAP2, confirmed by immunocytochemistry. These neurons are non-dividing, have a limited in vitro lifespan, and require careful handling to maintain viability. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | CD57 Mouse Neurons Hippocampal, Mouse Hippocampal Neurons, Hippocampal Neurons, Neurons, HNs, CD57 HNs |
| Species | CD57 Mouse |
| Cat.No | ABC-TC3328 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Neuron |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
CD57 Mouse Hippocampal Neurons serve as a reliable in vitro model to study hippocampal neurogenesis regulation, hippocampal synaptic dynamics, synaptic plasticity and neurodegeneration. They are widely employed in drug screening for neuroprotective agents, mechanistic studies of glutamate-mediated excitotoxicity, and electrophysiological investigations of ion channel function and synaptic transmission. Additionally, these neurons are suitable for modeling synaptic remodeling and assessing the impact of neuroinflammatory mediators on hippocampal circuitry.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).