CD57 Mouse Renal Tubular Epithelial Cells

Description

CD57 Mouse Renal Tubular Epithelial Cells are isolated from the renal cortex of healthy C57BL/6 mice and represent a key epithelial cell type lining the nephron tubules. These cells play a vital role in maintaining fluid, electrolyte, and acid-base balance through active transport and selective reabsorption. Cells are cryopreserved at early passages and are not suitable for extended passaging. Morphologically, these cells exhibit a typical cuboidal shape and grow as a polarized monolayer. Renal tubular epithelial cells are highly sensitive to nephrotoxins and oxidative stress and are often used to study acute kidney injury (AKI), chronic kidney disease (CKD), and drug-induced nephrotoxicity. They express key markers such as E-cadherin, aquaporin-1, and cytokeratin-18. Repeated freeze-thaw cycles or serial passaging should be avoided to maintain functionality. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.