For research use only
| Cat No. | ABL-TC0134 |
| Product Type | Mouse Ovarian Cell Lines |
| Cell Type | Epithelial |
| Species | Hamster, Chinese |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Ovary |
| Product Code | CHO K1; CHOK1; CHO cell clone K1 |
CHO-K1 Hamster Ovary Cells support protein production, gene transfection, and metabolic mutant selection in bioproduction and molecular workflows.
CHO-K1 cells are a subclone of the CHO cell line, derived from an adult Chinese hamster ovary biopsy in 1957. They harbor near-diploid (2n=20 with 4-6 structural aberrations) karyotype and are known for their high adaptability to suspension culture and serum-free media, making them a gold standard for recombinant protein production and biopharmaceutical research. CHO-K1 cells are adherent epithelial-like cells with fibroblast-like morphology, growing as monolayers with robust proliferation. CHO-K1 cells are widely used in biopharmaceutical production due to their rapid growth, ease of culture, and minimal chromosomal abnormalities. However, they lack the gene for proline synthesis, making them reliant on external proline for growth. Under specific culture conditions, these cells can be passaged for multiple generations, making them suitable for long-term experimental applications. They also express multiple glycosylation genes, which affect the quality of therapeutic proteins.
| Product Code | CHO K1; CHOK1; CHO cell clone K1 |
| Species | Hamster, Chinese |
| Cat.No | ABL-TC0134 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Ovary |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Ovarian Cell Lines |
The CHO-K1 cell line can be engineered to grow as adherent or suspension cells and has gained regulatory approval for the production of therapeutic recombinant proteins. CHO-K1 cells are an excellent host system for producing various biologics, including growth factors, hormones, monoclonal antibodies, interferons, and enzymes. Moreover, they are utilized in in vitro cancer research, especially for studying tumor glycosylation patterns. The popularity of CHO-K1 cells in protein production is due to favorable traits like rapid growth, easy cultivation, and genomic stability.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Ng JY, Chua ML, Zhang C, et al. Chlorella vulgaris Extract as a Serum Replacement That Enhances Mammalian Cell Growth and Protein Expression. Front Bioeng Biotechnol. 2020;8:564667. Published 2020 Sep 15. doi:10.3389/fbioe.2020.564667
CHO cells are Chinese hamster ovary cells, a widely used mammalian cell line in biotechnology. They are commonly employed for recombinant protein production, gene expression studies
