For research use only
| Cat No. | ABC-TC0137 |
| Product Type | Mouse Ovarian Cell Lines |
| Species | Hamster |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | CHO-SSTR1; CHO-SSR2 |
Species: hamster, Chinese female adult; Tissue: ovary; Transfected with the SSR2 somatostatin receptor; Original line: CHO-K1
CHO‑SSR2 is a stable, genetically engineered Chinese hamster ovary (CHO) cell line derived from parental CHO-K1 cells and transfected to express human somatostatin receptor 2 (SSTR2). These epithelial-like adherent cells grow in tight monolayers. They exhibit polygonal shape and demonstrate contact inhibition under confluent conditions. The cells maintain a near‑diploid karyotype (~20–22 chromosomes), and exhibit high transfection efficiency and genomic stability. CHO‑SSR2 demonstrates robust human SSTR2 expression, validated by ligand binding and functional inhibition of adenylate cyclase via Gi/Go proteins. The line is non‑tumorigenic in nude mice and is suitable for receptor pharmacology and imaging. STR profiling confirms lineage, and downstream signaling is confirmed through calcium mobilization or cAMP assays. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from mycoplasma, fungi, yeast, and bacteria.
| Product Code | CHO-SSTR1; CHO-SSR2 |
| Species | Hamster |
| Cat.No | ABC-TC0137 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Ovarian Cell Lines |
CHO‑SSR2 is an excellent tool for GPCR drug discovery focused on SSTR2-targeting therapeutic and diagnostic agents, including agonists, antagonists, and imaging tracers. Its stable receptor expression enables high-throughput ligand‑binding assays, downstream cAMP quantification, calcium flux, and receptor internalization studies. It is suited for screening somatostatin analogs and radiolabeled tracers, and supports co-transfection assays for signaling pathway and mutagenesis research. This cell line offers a reliable platform for translational pharmacology, biosensor development, and assay optimization involving somatostatin receptor-mediated pathways.
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