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COR-L23

Product Name

COR-L23

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Product Code

CORL23; COR-L23P; COR-L23/P; L23/P

Cat.No

ABC-TC0179

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

COR-L23 represents a prominent cell line derived from a pleural effusion of a 62-year-old male afflicted with giant cell anaplastic carcinoma of the lung, and was established in 1985. Characterized by a c-myc amplification and a kras mutation, this cell line holds significant relevance in cancer research. Notably, COR-L23 demonstrates tumorigenic potential in nude mice. In continuous culture, these cells exhibit an epithelial morphology, forming a monolayer. For subculturing, a regimen of splitting semi-confluent cultures at a ratio of 1:5 to 1:10 twice weekly is recommended, employing trypsin/EDTA as the dissociation agent.

 

Why choose COR-L23 from AcceGen?

COR-L23 cells sourced from AcceGen are characterized by their exceptional viability and quality. They are provided in a sterile state and are rigorously screened for the absence of contaminants, including mycoplasma, EBV, HBV, HCV, HIV-1, HIV-2, HTLV-1/2, and MLV. Moreover, the identity of these cells is verified through STR analysis, ensuring their authenticity and reliability for diverse research applications.

Disease

Lung Large Cell Cancer

Source Organ

Lung

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The COR-L23 cell line is instrumental in drug development endeavors targeting human lung cancer. It plays a pivotal role in evaluating the efficacy of agents such as alpha and recombinant gamma interferons (IFNs) on the growth of human lung cancer cell lines in in vitro settings. Moreover, COR-L23 is a valuable asset in the investigation of the multidrug resistance-associated protein (MRP) gene within human lung tumors. This research paves the way for the development of innovative therapies designed to surmount chemoresistance, offering promising prospects for more efficacious interventions in the realm of lung cancer treatment.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Human Lung Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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