For research use only
| Cat No. | ABC-TC0361 |
| Product Type | Human Uterine Cancer Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Product Code | CVCL_3380 |
Species: human, Black female 31 years old; Tissue: cervix; Tumor: carcinoma, epitheloid;
HeLa-422 is a genetically engineered subclone derived from the well-known HeLa cell line, which was originally established from a cervical carcinoma of a 31-year-old female. The HeLa-422 cell line was constructed by transfection with ER-pBact, a vector containing human estrogen receptor cDNA under the control of the human β-actin promoter, and confers resistance to G418. The cells exhibit epithelial-like morphology and form adherent monolayers when cultured in vitro. HeLa-422 cell line’s genomic stability and high transfection efficiency make it ideal for gene editing experiments, including CRISPR-Cas9 mediated knockouts and reporter gene assays. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | CVCL_3380 |
| Species | Human |
| Cat.No | ABC-TC0361 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Uterine Cancer Cell Lines |
HeLa 422 cell line is ideal for gene editing research, given its genomic stability and high transfection efficiency. These traits make it suitable for CRISPR/Cas9, reporter assays, and studies of cancer gene function. Its predictable response to editing tools simplifies the validation of targeted modifications. The cell line is also employed in viral oncology research, signal transduction analysis, and preclinical therapeutics evaluation.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
